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In preclinical studies, caffeine has demonstrated a protective effect against the occurrence of neural damage produced after administration of d-galactose [52], cadmium (Cd) [53], lipopolysaccharides (LPS) [54], or exposure to hyperoxia [55]

The collagen-derived compound collagen tripeptide induces collagen expression and extends lifespan via a conserved p38 mitogen-activated protein kinase cascade

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